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- El cuervo revista para adultos english registration#
- El cuervo revista para adultos english software#
Then, the socio-demographic variables of the population were measured and the diagnoses were verified.ĭuring the research, the INC Research Area Group supported the review of quality and veracity of the data provided in the registration forms.
El cuervo revista para adultos english software#
This period was chosen since, as of June 2007, the clinical and laboratory reports of INC patients were available in the Systems, Applications & Products in Data Processing (SAP) software this way, an adequate collection of information was guaranteed.Īfter obtaining a unified list, in April 2014, a review of the medical records was initiated, following approval (institutional registration INC-C410-3610-679) from the institutional Ethics Committees of the Faculty of Medicine of Universidad Nacional de Colombia and the INC. If the prevalence of defining malignancies in this group of patients is known, a hypothesis about the diagnostic opportunity of HIV/AIDS and the coverage of antiretroviral treatment in this population could be considered.Īn observational, analytical, cross-sectional study was performed, in which patients were selected from the databases of the Epidemiological Research, Public Health, Systems and Clinical Laboratory groups, as well as from the data of consultations and inter-service consultations of the Infectious Diseases Group in the same institution between 20.
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In addition, an evaluation was also performed on the association between the onset of defining neoplasms and the use of antiretroviral treatment, viral load and CD4 in the included patients. However, after the widespread introduction of the highly active anti-retroviral therapy (HAART) in the mid-1990s, a change in the distribution of neoplasms in this group of patients could be seen, in other words, the frequency of non-defining malignancies increased 6, 9, 10.Ĭonsidering the lack of studies on this condition in Colombia, this study intends to establish the prevalence of defining malignancies in adult patients with HIV/AIDS treated at the National Cancer Institute of Colombia (INC in Spanish) - national cancer reference center in the country- over a seven-year period. These neoplasms are usually observed in more than 70% of the cases worldwide 4, 5. Non-Hodgkin's lymphoma, Kaposi's sarcoma, and invasive cervical cancer report the highest relative risks, which are considered as the defining features of acquired human immunodeficiency syndrome (AIDS) 8. Possible theories have considered the immunosuppressive role of the virus, coinfection with other oncogenic potential viruses such as Epstein Barr or hepatitis C, and the presence of common risk factors between both diseases 3, 6, 7.
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Although a greater risk can be observed, there is no clarity about the direct pathophysiological role of the virus in the large group of tumors detected in this group of patients. Regarding the association of HIV with cancer, between 6% and 49% of patients with retroviral infection develop some neoplasm during the course of the disease 3 - 5. This, along with an average of 35% decrease in mortality rates observed during the past ten years, has caused an increase of the prevalence not only in relation to the number of new cases, but also to greater survival of infected individuals 1. In Colombia, the virus has a prevalence of 0.5-0.9% of the total population according to Unicef and UNAIDS reports 2. Numbers are not encouraging according to the report issued by the Joint United Nations Program on HIV/AIDS (UNAIDS) in 2014, 35 million people were infected around the world, with an incidence of 2.1 million new cases a year, in other words, about 6 000 new infections a day 1. The world witnessed an HIV/AIDS epidemic for four decades, after the first case was reported back in the 1980s.